Microbial conversion of avermectins by Saccharopolyspora erythraea: Hydroxylation at C-27.
نویسندگان
چکیده
منابع مشابه
Bacteriophages of Saccharopolyspora erythraea.
Five bacteriophages infecting only Saccharopolyspora erythraea (formerly Streptomyces erythreus) among 43 Streptomyces spp. tested were classified into two groups by phage-host relationships, restriction enzyme mapping, cohesive-end determinations, and Southern hybridizations. phi SE6, the most frequently isolated phage, produced clear plaques on all hosts tested, while phi SE45, phi SE57, phi ...
متن کاملMicrobial hydroxylation of 16α, 17α-epoxyprogesterone by Penicillium decumbens
Microbial transformation has been successfully applied in the production of steroid intermediates with therapeutic use and commercial value in pharmaceutical industry due to its high regio- and stereo-selectivity. As such, it is still important to screen microbial strains with novel activity or more efficient abilities in the development of the commercial steroid industry. Biotransformation of ...
متن کاملGenome Sequence of Saccharopolyspora erythraea D, a Hyperproducer of Erythromycin
Saccharopolyspora erythraea is a Gram-positive bacterium that can produce antibiotics. However, this microorganism must often be genetically improved for higher production before it can be used in an industrial setting. Here, we report the whole-genome sequence of the industrial hyperproducer strong mutator Saccharopolyspora erythraea strain D.
متن کاملSynthesis of Erythrochelin: A Hydroxamate-Type Siderophore from Saccharopolyspora erythraea
Abstract Erythrochelin, a hydroxamate-type siderophore produced by Saccharopolyspora erythraea, is synthesized for the first time. A key building block of erythrochelin containing the 2,5-diketopiperazine ring is prepared by intramolecular cyclization of the corresponding dipeptide precursor derived from two kinds of protected δ-N-hydroxy-L-ornithines. Consecutive condensation of the building b...
متن کاملEnhancing the effect of soybean oil refinery byproducts on erythromycin production by Saccharopolyspora erythraea
Erythromycin production is clearly enhanced by the addition of vegetable oils. However,whether this positive effect is brought about by the triglyceride or non-triglyceride fraction, isnot clear. The non-triglyceride portions of the oils accumulate in the waste during the refiningprocess leaving mainly triglycerides in the refined oil. In this research, sub-fractions of soybeanoil, including le...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1994
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.47.372